Charlotte 49ers vs South Florida Bulls Prediction, Odds and Picks for Today, 03/14/26

The No. 5 seed Charlotte 49ers dispatched the No. 4 seed UAB Blazers in their home city, ruining the possibility of all four of the top seeds facing off over the weekend. Now, Charlotte gets to shoot its shot against the top seed South Florida. Charlotte won 83-78 as a 5.5-point underdog against UAB, and it is 2-0 straight up and against the spread (ATS) in this tournament, while going 6-2 ATS in the previous eight outings. Of course, one of those two non-covers came in the regular-season finale at Yuengling Center in Tampa, an 83-60 loss to South Florida on last Sunday. Charlotte had lost the final three regular-season games, while going 2-7 SU from Feb. 4-March 8, so not many saw a Cinderella run in the conference tournament coming.

USF earned the top seed in the American, and it has won nine in a row since Feb. 4, while covering four of the past five outings, and six of the previous eight. The Under is 7-1 in the past eight outings, in case you’re looking for a same-game parlay (SGP) opportunity. Based on USF’s 23-point romp in the regular-season finale it would be easy to lay the big points with the Bulls. But, that’s a lot of points in a conference semifinal, and the 49ers are playing with renewed confidence.

Charlotte +14.5 (-115) at time of publishing. Playable to +13.5.