Clemson Tigers vs BYU Cougars Prediction, Odds and Picks for Tuesday, 12/09/25

The BYU Cougars and the Clemson Tigers will clash in a Big 12-ACC showdown from Madison Square Garden on Tuesday. The Cougars are 7-1 SU this season and in the midst of a 4-1 SU and ATS run over their last 5 games. Meanwhile, the Tigers are coming off a loss to Alabama, which snapped a 4-game winning streak, although they covered the +9 spread and have now gotten to the window for spread bettors 3 games in row following a 4-game non-cover streak. Whenever I see a college basketball game at MSG that doesn’t involve St. John’s, I’m interested in the under. Neutral-site college basketball unders have a profitable history at The Mecca due to unfamiliar sight lines and difficulty with depth perception compared to the smaller arenas in which most of these teams play, and I expect that to come into play yet again in this matchup.

BYU can score in a myriad of ways, but the Cougars love to play in transition – sitting in the 93rd percentile in transition frequency according to Hoop-Explorer. Despite just surrendering 90 points to Alabama last time out, Clemson is typically very good at limiting transition opportunities and slowing down the pace of games. In fact, only 8 teams force a longer average possession length than Clemson. The Tigers also have size to contest BYU’s jump shots and limit the Cougars on the offensive glass. 

After letting Alabama control the game the way it did, I expect head coach Brad Brownell’s squad to be more deliberate in terms of pace of play. The Tigers are seventh nationally in turnover rate, so they should be able to grind possessions deep into the shot clock. When betting an under, that deliberate pace pairs well with inconsistent and inefficient shooting – particularly from the perimeter – and that’s Clemson’s MO. The Tigers are shooting just 43.5% outside of their home gym, and they have connected on fewer than 33% of their perimeter shots this season. Scoring may be at a premium here; lean to the under. 

Clemson vs BYU prediction: Under 150.5 (-110) at the time of publishing. Playable at that number.

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