Creighton Bluejays vs Butler Bulldogs Prediction, Odds and Picks for Today, 03/04/26

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The Creighton Bluejays will travel to Indianapolis on Wednesday night for a Big East Conference game against the Butler Bulldogs. This will be the last home game for the Bulldogs before they head to DePaul for their season finale. This is Creighton’s last game of the season before the Big East Tournament, and they will need to win the tourney if they want to make the big dance. They have lost 5 of their last 6 games and I do not see them getting back on track here. Butler has a solid 10-6 record at home, and I expect them to finish off their regular season with a win here at home. As a result, I’ll be backing Butler to cover the 2.5-point spread.

Simply put, the Bulldogs have been playing better basketball than Creighton as of late. Butler is ranked 63rd nationally at Bart Torvik since February 1, compared to Creighton at #82. Butler’s 56th-ranked offense since February 1 should be able to be outscore a Creighton offense that is ranked just 100th nationally. Butler lost by just 4 points on the road at Creighton earlier in this season and I expect them to get revenge in the rematch.

Creighton vs Butler prediction: Butler -2.5 (-110) available at time of publishing. Playable to 3.

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