Indiana Hoosiers vs USC Trojans Prediction, Odds and Picks for Today, 02/03/26

The Indiana Hoosiers will travel to Los Angeles on Tuesday night for a Big 10 Conference game against the USC Trojans. The Hoosiers are looking to sweep their west coast trip after beating UCLA on Saturday in double overtime. Indiana has won three straight games and are a slight underdog against USC in this game. The Trojans are coming off a win against Rutgers in their last game and will to get back to .500 in conference play. I am going to back the home team here and take USC -1.

USC -1 is my best bet of the game because I believe their defense will good enough to slow down Indiana’s offense. Indiana’s offense is ranked #29 in adjusted offensive efficiency, but they rely heavily on the three-point shot. 39.2 percent of Indiana’s points are from three and that is ranked #23 in the country, according to KenPom. USC is very good at defending the three-point line and that could cause issues for Indiana. The Trojans offense also gets to the free throw line better than anyone and that should influence this one. USC’s offense is ranked #2 in free throw rate while Indiana’s defense is ranked #248. Take USC here.

*USC -1 available at time of publishing. Playable at -2*