Iowa Hawkeyes vs Indiana Hoosiers Prediction, Odds and Picks for Today, 01/17/26

The Iowa Hawkeyes will travel to Bloomington on Saturday afternoon to play a Big Ten game against the Indiana Hoosiers. Both Iowa and Indiana have first-year coaches looking to get their programs to the NCAA Tournament, and this game could have a massive effect on that. The Hawkeyes have lost 3 straight and Indiana has dropped 2 on the trot, so the urgency will be in the air on Saturday. It should be a very close game as the spread suggests, but I expect Indiana to pull out the win.

Indiana is currently -2.5 on its home floor and the Hoosiers to cover are my best bet of the game because their offense should be able to score efficiently. Iowa is ranked highly in adjusted defensive efficiency on KenPom, but its effective field-goal percentage and 2-point defense is outside the top 100. Indiana’s offense is ranked #22 in effective field-goal percentage and #13 in 2-point percentage; Iowa’s defense is ranked #105 and #173, respectively. I do not see Iowa stopping the Indiana offense enough for the visitors to cover. Let’s roll with Indiana ATS.

Iowa vs Indiana prediction: Indiana -2.5 (-110) available at time of publishing. Playable to -3.

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