Appalachian State Mountaineers vs Old Dominion Monarchs Prediction, Odds and Picks for Today, 10/25/25

The Appalachian State Mountains head to the Tidewater region to take on the Old Dominion Monarchs in a Sun Belt Conference Game at S.B. Ballard Stadium in Norfolk, Virginia. App State comes into this contest off a 45-37 loss at home against Coastal Carolina last time out as a 10.5-point favorite. The Mountaineers have been solid offensively, averaging 39.0 PPG in the past 2 games, but the defense has allowed 38 or more points in 3 of the past 5 outings. The Over is 4-1 in the past 5 games. The Mountaineers won last season’s meeting in Boone by a 28-20 score, cashing the under. The total has gone low in each of the 5 meetings since September 26, 2015.

Old Dominion was boat-raced by James Madison last time out, falling 63-27, and it has allowed 111 points in the past 2 games. On the other side, ODU has scored at least 21 points in each of its last 6 games. The over is 4-1-1 in the past 6 games, too. ODU has trouble stopping the run, allowing 194.3 yards per game. Despite the series trends suggesting an under result, the best course of action if going over on the total in this Sun Belt battle.

Appalachian State vs Old Dominion prediction: Over 63 (-110) at time of publishing. Playable to 64.5.

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