Baylor Bears vs Arizona Wildcats Prediction, Odds and Picks for Today, 11/22/25

One of the more fascinating games in the Week 13 slate comes in the Big 12, where the Baylor Bears will square off against the Arizona Wildcats in a game that should feature plenty of points in Tuscon. Baylor has been a relative disappointment compared to preseason expectations at the onset of the season, but the Bears still have an offense that is capable of putting up points in bunches, even in a losing effort. After all, we just saw Baylor finish with well over 500 yards of offense against Utah a week ago in a game where the Bears were thoroughly dominated on the scoreboard but still finished with 28 points. There’s no reason that Sawyer Robinson and company shouldn’t see more success on Saturday, even with Arizona’s defense coming off a solid game against Cincinnati a week ago. The Wildcats are an improved defense and currently sit inside the top 30 nationally in a variety of key areas, but it’s important to consider that Arizona has played a few of the worst offenses in the Big 12 (Oklahoma State, Colorado, Kansas State) in advantageous spots, which has likely juiced up those metrics a bit. With that in mind, the Baylor offense should remain consistent and score at least 27 points in this Big 12 clash.

As for the hosts, the Arizona offense got off to a pretty slow start in September, but the Wildcats have found their stride over the last 6 games as Noah Fifita and company have won 4 of 6 while averaging nearly 34 points per game over that span. This should once again be a very favorable matchup against a Baylor defense that has been the weakness of the team all season long. Baylor enters this game ranked 117th in success rate allowed and points per drive allowed (CFB-Graphs), so it’s hard to see the Wildcats stumbling a bit on offense at home. Ultimately, this projects to be a back-and-forth affair with plenty of lead changes, so I’ll grab the over in a game that should be a barnburner. 

Baylor vs Arizona prediction: Over 62 available at time of publishing. Playable to 62.5

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