Florida Atlantic Owls vs South Florida Bulls Prediction, Odds and Picks for Tomorrow, 10/18/25

The FAU Owls make the cross-state trek to Raymond James Stadium to battle the ranked USF Bulls in Tampa. USF’s offense has been super explosive, going for 54 or more points in three straight outings, while averaging 58.5 points per game (PPG) in the past two American Conference games against Charlotte and North Texas. It has covered both of its games as a favorite of 21 or more points, too, while cashing the Over in four in a row. QB Byrum Brown leads the team with 1,439 passing yards, 13 touchdowns and five interceptions, while also leading with 364 rushing yards and five scores. If FAU is to sniff an upset, it all starts with containing Brown, or at least limiting him somewhat.

The Owls looked dead in the water after back-to-back losses at FIU and home to Memphis, both by double digits. However, FAU surprised Rice 27-21 on the road, and it followed that up with a 53-33 win over UAB, showing a little offensive explosiveness of its own. In fact, the Owls are good for 26 or more points in each of the past five games since a 39-7 loss at Maryland in the opener. The Over is 4-1 in the past five games, but the total on this game is much to high. However, FAU catching more than three touchdowns is huge, and if you can get 21 and a hook, that could be a very important half-point. FAU should be able to keep USF within arm’s length, but its defense leaves a lot to be desired, so be ready to sweat. The road team has won and covered the past three meetings in this series.

FAU +21.5 (-115) at time of publishing. Playable to 21.