Florida State Seminoles vs NC State Wolfpack Prediction, Odds and Picks for Today, 11/21/25

The Florida State Seminoles hit the road for Raleigh on Friday night, and this battle against NC State will come with bowl eligibility for the winner. Both teams enter with 5 victories, 1 short of bowl eligibility. FSU has had its issues on the road this season. It all started with a stunning 46-38 loss in overtime at Virginia, and the season has spiraled from that point. It is 0-3 SU and ATS in 3 game away from home, including a 20-13 loss at Stanford on October 18 as a 17.5-point favorite and a 24-10 loss at Clemson in the most recent trip on November 8. That’s just 11.5 PPG scored on offense, with 22.0 PPG allowed on defense.

For NC State, it was humbled 41-7 at Miami last Saturday, a disappointing result after 2 weeks off following a massive 48-36 win in Raleigh against previously unbeaten Georgia Tech on November 1 as a 5.5-point underdog. Still, NC State is just 1-3 SU and ATS in the past 4 games, but at home it is 4-1 SU, and 3-1 ATS in the past 4. Florida State hasn’t shown an ability to win on the road, so let’s keep rolling with the opponent in those spots, especially since the Wolfpack are catching points at home. NC State is 5-2 ATS in the past 7 in the series, too, winning each of the past 3 meetings in Raleigh since November 3, 2018.

Florida State vs NC State prediction: NC State Wolfpack +4.5 (-110) available at time of publishing. Playable to +3.5.

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