Jacksonville State Gamecocks vs Middle Tennessee Blue Raiders Prediction, Odds and Picks for Today, 10/29/25

The Jacksonville State Gamecocks head to Murfreesboro looking to stay unbeaten in Conference USA play against the struggling Middle Tennessee Blue Raiders. This is not the place Jacksonville State can afford to stub its toe, if it hopes to keep it conference championship game appearance hopes alive. The Gamecocks have struggled on the road, winning just once in four tries this season, but it did post a 29-27 win at Sam Houston on Oct. 9 in the most recent try on the road. And, an impressive 38-25 win over Delaware two weeks ago helped Jax State cover as 3-point underdogs, halting an 0-4 against the spread (ATS) skid.

The Gamecocks have had two full weeks to rest bumps and bruises, including QB Caden Creel, who has been nursing an arm injury. Whether or not Creel is ready, or it is former Rutgers and Kentucky QB Gavin Wimsatt starting, doesn’t matter. Middle Tennessee has been bad, losing all three games at home, while going 1-2 ATS in those outings. One of the losses came by 20 points against FCS Austin Peay, too. However, while all of that sounds grim, the Blue Raiders have been better lately, and the past three losses have each been by one score, and an average of just 4.3 PPG. Be careful here, and proceed with caution. However, Jacksonville State is the better team, and it should get the job done.

Jacksonville State vs Middle Tennessee prediction: Jacksonville State -5.5 (-110) available at time of publishing. Playable to -6.5.

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