Kennesaw State Owls vs Jacksonville State Gamecocks Prediction, Odds and Picks for Today, 12/05/25

The Kennesaw State Owls hit the road to battle the Jacksonville State Gamecocks in the Conference USA championship game at AmFirst Stadium in Jacksonville, Alabama. The Owls kept their bid alive for the title game by holding off Liberty 48-42 in overtime in the regular-season finale, covering as 2.5-point favorites. The Owls were just 1-2 against the spread (ATS) in the final three road games of the season, including a 35-26 loss at Jacksonville State on Nov. 15 as 3.5-point favorites. Kennesaw State deserved a better fate in that game, posting 32 first downs, to just 18 for Jax State. It also had 579 total yards of offense, to just 451 for the Gamecocks. However, the Owls turned it over four times, while the Gamecocks didn’t have any miscues.

Quarterback play as the difference, as Kennesaw’s Amari Odom threw three picks, while running for 51 yards and a score. Jacksonville State’s Caden Creel threw for 137 yards, while running for 127 yards and a pair of touchdowns. RB Cam Cook also ran for 132 yards and a touchdown, giving the Gamecocks a pair of 100-yard rushers. Venue will be the difference in this game, as the Gamecocks host this game. Will Kennesaw turn it over four times again? Probably not. However, the Gamecocks will benefit having this game at home, winning a close game.

Jacksonville State +2.5 (-110) at time of publishing. Playable to +1.5.