Minnesota Golden Gophers vs Oregon Ducks Prediction, Odds and Picks for Friday, 11/14/25

We have a Big Ten tilt between a couple of unfamiliar foes on Friday as the Oregon Ducks are set to host the Minnesota Golden Gophers in a game that doesn’t project to be all that close on paper. However, even though I’m not all that high on this Minnesota team, I’m much more inclined to back the Gophers on the road in what is one of the best situational spots on the board in this Week 12 slate. On one side, the Gophers are in the midst of a solid season, having just qualified for bowl eligibility after defeating Michigan State on November 1. Now, with Minnesota coming off a much-needed bye week prior to this extended road trip, PJ Fleck should have his team prepared to play in what is a natural get-up spot for a rested and ready Gophers side. 

Conversely, the Ducks are in a pretty brutal letdown spot after knocking off Iowa on the road in what was arguably the most important win of its season to this point. Now, Dan Lanning’s side will have to travel all the way to the northwest for a bizarre matchup against a new conference foe that they couldn’t possibly care all that much about, all while staring at a massive potential College Football Playoff elimination game against USC on deck. It shouldn’t surprise anyone if the Ducks come out pretty flat in a spot in which they could still be a bit hungover from last week’s victory in dramatic fashion at Kinnick Stadium. Oregon certainly looks to be one of the 10-12 best teams in the nation to this point, but it’s also worth considering that the Ducks were extremely banged up a week ago and could be without as many as 5 starters on offense this week if those injuries carry over. With that in mind, it wouldn’t surprise me at all if Oregon approached this game with a bit more trepidation and kept things pretty close to the vest. As a result, the Gophers could certainly keep things within the number in a game with a fairly low total, so I’ll certainly take the points with Minnesota on Friday. 

Minnesota vs Oregon prediction: Minnesota +26.5 available at time of publishing. Playable to 25.5

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