Missouri State Bears vs Middle Tennessee Blue Raiders Prediction, Odds and Picks for Tomorrow, 10/08/25

Missouri State hits the road for their first conference road game. The Bears have alternated loss and wins in the first five games, while going 1-1 straight up (SU) and against the spread (ATS) in its first two road games. The first game was a 73-13 loss at USC, failing to come close as a 35.5-point underdog, while winning outright as a 7-point underdog in a 21-20 win at Marshall on Sept. 6. The Bears are 3-1 ATS in the past four games, while cashing the Under in each of those outings. That’s worth filing away for a same-game parlay (SGP). The Bears have scored 22 or fewer points in four of five games, while allowing 28 or fewer points in the past four since that 73-point debacle against the Trojans.

Middle Tennessee started the season with a 34-14 loss at home against FCS Austin Peay despite being a 15-point favorite as the Under (53.5) cashed, and the Blue Raiders are a dismal 1-4 ATS. The only exception was a stunning 14-13 road win at Nevada as a 9-point underdog as the Under cashed. The Blue Raiders are 0-2 SU/ATS in two home games, and it suffered a 24-16 loss at Kennesaw State in the league opener last time out on Sept. 27 as the Under (53.5) came through. Take Missouri State laying the points for your best bet, but take the Under, too, as part of an SGP.

Missouri State -2.5 (-110) at time of publishing. Playable to -3.