New Mexico Lobos vs San Jose State Spartans Prediction, Odds and Picks for Today, 10/03/25

The New Mexico Lobos hit the road for San Jose State for the Mountain West opener, and the Lobos are brimming with confidence. UNM has won 3 straight games and is a healthy 3-1 against the spread (ATS) in 4 games this season. The last time it was in the state of California, New Mexico routed UCLA 35-10 in a game which ended up being the last straw for Deshaun Foster as head coach for the Bruins. There is no shame losing to the Lobos, though, as this team is playing well. It’s lone loss was a 34-17 setback at Michigan, covering a 34.5-point number. UNM has a balanced attack, posting 174.0 rushing yards, and 217.0 passing yards per game.

San Jose State is 6-0 ATS in the past 6 meetings in this series since Dec. 23, 2006, including a 52-24 rout in Albuquerque in the last meeting on October 14, 2023. But, Ken Niumatalolo’s team is just 1-3 SU this season, and 0-2 ATS at home, including a 16-14 setback to lowly Central Michigan in the opener on August 29. San Jose State has allowed 28 or more points in 3 in a row to Texas, FCS Idaho and Stanford. The Longhorns game is excusable, but the Spartans D was ugly in the past 2 games. New Mexico is an underrated team with no amazing parts, but also no glaring weaknesses. Take UNM to get the job done as slight underdogs.

New Mexico vs San Jose State prediction: New Mexico ML (+115) available at time of publishing. Playable to +105.

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