North Texas Mean Green vs Rice Owls Prediction, Odds and Picks for Saturday, 11/22/25

The North Texas Mean Green head from Denton to Houston to battle the Rice Owls in Houston in an intra-Texas American Conference battle. UNT is looking to keep it possible, but faint, hopes alive for spot in the College Football Playoff, too. The Mean Green have been one of the most potent offenses in the nation, too, going for 489.6 total yards and 307.3 passing yards per game, both ranking sixth in the country. It also has 182.3 rushing yards per game, 40th in the country, while ranking No. 1 overall with 45.3 PPG. Defensively, North Texas does struggle to stop the run, allowing 202.7 yards per game, and that’s been an Achilles heel.

For Rice, it cashed the Under in a 24-17 win over UAB last time out, but the Over has cashed in three of the past four games, with the defense allowing 27 or more points in four of the past five outings. That’s ominous with North Texas looming on the horizon. The Owls really struggle offensively, although it has posted 211.1 yards per game, ranking 18th in the country, and that’s bad news for UNT’s struggling rushing defense. But, Rice allows 27.9 PPG, ranking 89th in the country, and that means North Texas should come close to its season average in points. If so, the Over should be a slam-dunk play in the Space City.

Over 55.5 (-110) at time of publishing. Playable to 57.5.