Notre Dame Fighting Irish vs Arkansas Razorbacks Prediction, Odds and Picks for Saturday, 09/27/25

One of the more entertaining games on this weekend’s college football card comes in SEC country, where the Arkansas Razorbacks will host the Notre Dame Fighting Irish from Fayetteville. The Hogs are coming off a pair of demoralizing losses against the likes of Ole Miss and Memphis, with both defeats coming on the road by a combined 7 points. In fact, one could certainly argue that Arkansas should’ve won at least one, if not both of those games, especially since they led in the 4th quarter against Memphis and were just a few yards away from a potential game-winning touchdown against Ole Miss. With that in mind, we’re getting a bit of value on Arkansas at home in a game where Talen Green and this electric offense (4th in success rate, 1st in Early Downs EPA and 5th in 3rd and 4th down success rate) should be able to score early and often against a Notre Dame defense that has struggled mightily this season with Chris Ash at the controls. In fact, the Irish are just 101st in passing success rate allowed and 87th in points per drive allowed, so there should be plenty of scoring opportunities for Arkansas to put up points.

On the other side of the ball, the Arkansas defense has just as many problems as its offense, and the Hogs will be going up against a Notre Dame offense that has been clicking on all cylinders of late, particularly on the ground with Jeremiyah Love leading the way out of the backfield. However, this is still a unit that should be able to hold up a bit more than its counterparts in the passing game, especially considering that Arkansas has already had to play an elite passing attack in Ole Miss. Neither defense is likely to cover itself in glory in this matchup, but I have a bit more faith in the home team to give an all-out effort in what is surely a desperate spot for the Razorbacks following a pair of demoralizing losses. Ultimately, this game should produce plenty of fireworks, but Arkansas should stay within a possession, and could even spring the upset.

Notre Dame vs Arkansas prediction: Arkansas +5.5 available at time of publishing. Playable to Arkansas +4.

Now you can bet any of our Notre Dame vs Arkansas predictions at FanDuel Sportsbook, which has a great new-customer offer to take advantage of. If you sign up for FanDuel right now, you earn a welcome bonus worth up to $300 if your first $5 bet wins! 🔗 to join FanDuel right now and learn more.