Ohio Bobcats vs Buffalo Bulls Prediction, Odds and Picks for Friday, 11/28/25

The Ohio Bobcats hit the road for Western New York to take on the Buffalo Bulls in the regular-season finale for both of these Mid-American Conference (MAC) teams. The weather is going to be rather unique, too. While the snow showers are expected to taper off in the morning hours, there is still a chance of flurries at kickoff with temperatures around freezing. The big story will be the wind, however, as they’ll be sustained winds from 19-22 MPH, with gusts to gale force. In fact, a Midwest weather system is kicking off, and there is expected to be a seiche on Lake Erie, which essentially moves feet of water, exposing the western side of the lake’s bed, while piling up waves and water on the eastern shores. There could be waves up to 20 feet in western New York. While that won’t necessarily impact the game, it speaks to the conditions and strength of the wind.

We should have a mostly ground-based attack from both sides, and that’s good news for Ohio. RB Sieh Bangura is a stud in the MAC, and Ohio is 23rd in the nation with 216.9 rushing yards per game. For Buffalo, it is a poor running team, ranking 100th in the nation, but it is solid against the run, as the defense allowing just 138.8 yards per game to rank 41st. In fact, the Buffalo defense has a whole has been very fierce. Look for points to be at a premium in Saturday’s MAC finale.

Under 44 (-110) at time of publishing. Playable to 41.