Purdue Boilermakers vs Minnesota Golden Gophers Prediction, Odds and Picks for Today, 10/11/25

The Purdue Boilermakers hit the road for the Twin Cities to battle the Minnesota Golden Gophers for a Big Ten conference battle. While Purdue has shown signs of life on offense, going for 28.5 points per game (PPG) in the past 2 games and at least 27 points in 4 of 5 outings this season, the defense has been torched for 99 points in the past 2 games — losses to Illinois and Notre Dame.

For Minnesota, it was trucked 42-3 at Ohio State last week, and it has allowed 27 or more points in 3 straight outings, going 0-3 ATS in the span. The over has cashed in 4 straight games, as the Gophers have allowed 21.4 PPG while going for 27.4 PPG on offense. The over has a slight 3-2 edge in the past 5 meetings in the Twin Cities, while going 7-3 in the previous 10 installments dating back to Oct. 18, 2014. The over has hit in the past 2 games for Purdue, too, while Minnesota has cashed high in four in a row. We’ll go high on this total, as neither of these teams can be trusted against the spread.

Purdue vs Minnesota prediction: Over 49.5 (-110) at the time of publishing. Playable at that number.

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