San Diego State Aztecs vs Fresno State Bulldogs Prediction, Odds and Picks for Saturday, 10/25/25

The San Diego State Aztecs hit the road for The Valley to battle the Fresno State Bulldogs on Saturday afternoon in a Mountain West Conference battle. The Aztecs offense has come alive in the past two games, racking up 44.5 points per game (PPG) in the past two games, while posting 34 or more points in three of the past four outings. The Aztecs are 4-0 against the spread (ATS) in the past four games, too, if you’re looking for a Same-Game Parlay (SGP) opportunity. A high-powered rushing offense with 180.2 rushing yards per game, coupled with a suffocating defense with 259.7 total yards, 161.2 passing yards, 98.5 rushing yards and 12.2 points per game allowed is a great recipe for victory.

The Fresno State Bulldogs had racked up five straight wins from Aug. 30-Oct. 4, but they received a dose of reality at Colorado State two weeks ago in a 49-21 loss as 5.5-point favorites. It was the first time Fresno State’s defense has really struggled badly. The Bulldogs are 0-3 ATS in the past three games, however, and that’s where we’ll focus. The Bulldogs have won four of the past six meetings in this series, but San Diego State is 4-1 ATS in the past five meetings since Nov. 17, 2018. Let’s roll with the confident Aztecs to get the job done, and feel confidently in backing them.

San Diego State -3 (-110) at time of publishing. Playable to -4.5.