Troy Trojans vs Clemson Tigers Prediction, Odds and Picks for Today, 09/06/25

After starting the season as one of the favorites to win the College Football Playoff, the Clemson Tigers lost their opening game of the year 17-10 against the LSU Tigers. LSU’s defense made Clemson’s offense look average all game long. Quarterback Cade Klubnik finished with only a 50% completion percentage and no touchdowns, and Clemson’s offense as a whole was held to only 261 yards. In Week 2, Clemson will have the opportunity to make things right and prove their talent against the Troy Trojans from the Sun Belt Conference. Troy is 1-0 after defeating Nicholls 38-20. Troy trailed this game 17-7 halfway through the 3rd quarter before turning it on late. The Trojans were led by quarterback Goose Crowder. Crowder finished the game with 3 touchdowns thrown. Troy is a heavy underdog going into Saturday, but it’s not uncommon for a team from the Sun Belt to put up a good fight against a Power Four school.

The main storyline going into this game for Clemson is its offense. Yes, in Week 1 the Tigers were going against an LSU defense that may finish as a top unit in the nation this season, but Clemson’s offense still left more to be desired. Klubnik is entering his senior year and is expected to have his best season with an experienced unit under head coach Dabo Swinney. Klubnik struggled with consistency in the face of LSU’s exotic blitzes and pass rush, but the Heisman hopeful should be able to get into more of a rhythm against Troy. Clemson should also be able to improve its rushing game in Week 2. The run was nearly nonexistent against LSU, gaining 31 yards on 20 attempts. Adam Randall transitioned this offseason from receiver to running back, and this Saturday can be a good opportunity for him to show why Swinney was comfortable making that move instead of using the transfer portal. All things considered, this is a get right spot for Clemson’s offense. I think Troy will be able to manage some points on their end as well, putting this game over the total.

Troy vs Clemson prediction: Over 51.5 (-110) is available at the time of publishing. Playable at that number.

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