Tulsa Golden Hurricane vs Memphis Tigers Prediction, Odds and Picks for Saturday, 10/04/25

The Tulsa Golden Hurricane heads to the banks of the Mississippi River for a battle with the Memphis Tigers in an American Conference battle. The Tigers have scored at least 28 points in all five games to date, and they scored a season-high 55 points in a victory at FAU last weekend as a 14-point favorite. Memphis is not only unbeaten in five games, it is 5-0 against the spread (ATS). That includes a thrilling 32-31 comeback victory over Arkansas of the SEC last time it was at home on Sept. 20, cashing as a 7-point underdog. It has been a favorite of 14 or more on three separate occasions, and Memphis has won those three games by a margin of 28.7 points per game.

For Tulsa, it suffered a 31-14 loss at home to Tulane as a 14.5-point underdog as the Under (52) cashed. The Under is 4-1 in five games for Tulane, as the offense has scored 23 or fewer points in all four games against FBS opponents, while allowing 21 or fewer points in three of five outings. Memphis should be able to rack up plenty of offense in this game, but Tulsa’s Under run is why you need to shy away from the total. Instead, back Memphis, who is 5-0 ATS, and keep rolling with the Tigers until that cover wave crashes.

Memphis -20.5 (-110) at time of publishing. Playable to -21.