Tulsa Golden Hurricane vs Oklahoma State Cowboys Prediction, Odds and Picks for Friday, 09/19/25

The Tulsa Golden Hurricane hit the road to battle the Oklahoma State Cowboys at Boone Pickens Stadium in Stillwater. Oklahoma State leads the all-time series 44-28-5, including 10 straight victories in the series since Sept. 11, 1999, including a 45-10 win last season on Sept. 14 in Tulsa. Oklahoma State is 6-1 against the spread (ATS) in the past seven meetings, with the Under going 4-0.

Tulsa dropped a 42-23 game at home against Navy, failing to cover as a 14-point underdog as the Over (53) cashed. The Under is 2-1 in three games to date, however. For Oklahoma State, the last time we saw it on the football field, it was blasted 69-3 at Oregon as a 28.5-point underdog. Oklahoma State will be champing at the bit to get back on the field after a bye win Week 3. It is 0-2 against the spread (ATS) so far this season, and it’s hard to understand why the Cowboys are favored by two touchdowns in this one. The Golden Hurricane might not win, but a team which was dusted by 66 last time out has no business laying double digits to anybody. Take the Golden Hurricane plus the points, going against the series trends.

Tulsa +13 (-110) at time of publishing. Playable to +12.5.