UTSA Roadrunners vs Colorado State Rams Prediction, Odds and Picks for Today, 09/20/25

The Roadrunners of UTSA hit the road to battle the Rams of Colorado State at Canvas Stadium in Fort Collins. UTSA lost its first two games at Texas A&M and at home to Texas State, while topping FCS Incarnate Word last time out by a score of 48-20. The over has cashed in all three games, with UTSA going for at least 24 points in each of them, and it has allowed 42.5 PPG against its two FBS opponents.

Colorado State has struggled a bit on offense, as losing WR Tory Horton, who is now with the Seattle Seahawks, was a big blow to the passing game. It lost 38-21 in the opener at Washington, before topping FCS Northern Colorado just 21-17 at home on Sept. 6. The key here is that Colorado State has had two weeks to prepare, so it is a little curious to see the Rams as underdogs at home. More importantly, though, the Rams cashed the over at Washington, allowing 38 points, while UTSA has hit the over in all three games. SGP players will want Colorado State and the Over, while the most important part is playing high on the total.

UTSA vs Colorado State prediction: Over 59.5 (-110) at time of publishing. Playable to 60.5.

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