MLB Picks

The home of free expert MLB picks every day of the 2025 MLB season. The bumper 162-game season returns in 2025, seeing a total of 2,340 regular season games played, plus the MLB Postseason. Get free MLB expert picks on all of the top MLB games today, right through to the MLB World Series.

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12:35 PM ET
Yesterday
MARQ, MLBN, SNPT
Chicago Cubs
Pittsburgh Pirates
Cubs
Pirates
Money Line Pick
CHI Cubs Win(-155)

The Chicago Cubs will go for the sweep on Wednesday as they look to wrap up their 3-game series against the Pittsburgh Pirates. Taking the mound for the Cubs will be the left-hander, Matthew Boyd, who enters with a 13-8 record and a 3.05 ERA. Boyd has struggled recently, going 2-2 with a 5.97 ERA in his last 5 starts. 

For the Pirates, Johan Oviedo will get the start, entering with a 2-0 record and a 2.81 ERA. Oviedo has pitched well and may be able to limit the number of runs scored by the Cubs, but the Pirates are averaging just 2.2 runs per game over their last 10. The Cubs’ offense has been slightly better, averaging 3.6 runs per game. Pittsburgh has also been among the league’s worst against left-handed pitching, batting just .218 — which puts them 29th in the majors. The Cubs have been the better team all season and I don’t think they’ll have any issues in this matchup against the Pirates. 

Cubs vs Pirates prediction: Cubs ML (-155) available at time of publishing. Playable at that number.

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Jason Fragomeni
2:10 PM ET
Yesterday
MASN 2
Baltimore Orioles
Chicago White Sox
Orioles
White Sox
Money Line Pick
BAL Orioles Win(-135)

I favor the Baltimore Orioles over the Chicago White Sox as the teams face off Wednesday. Tyler Wells is the scheduled starter for the Orioles, marking his 3rd start of the season. His first was on the 2nd of this month, resulting in 5 innings of 2-run ball against a playoff-caliber Padres lineup. He followed that outing up with 6.2 innings of 1-run ball against a weaker Pirates lineup. Now Wells faces an even weaker White Sox unit in hopes that he can continue his strong form.

Martin Perez is set to start this game for Chicago. The veteran southpaw hurler has made 10 appearances for the south side this season, totaling 52.1 innings of work. His 3.27 ERA in that stretch is a solid mark, especially for a White Sox starting pitcher, but it is a mark that has jumped over a run in his last 2 outings alone. While Baltimore is not the greatest lineup against left-handed pitching, they are still my preferred offense in this matchup, and I lean towards a Baltimore win.

Baltimore Orioles vs Chicago White Sox prediction: Orioles ML (-135) available at time of publishing. Playable at that number.

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Javan Shouey
4:45 PM ET
Yesterday
MASN
Atlanta Braves
Washington Nationals
Braves
Nationals
Money Line Pick
ATL Braves Win(-155)

I lean towards a win for the Atlanta Braves on Wednesday as they take on the Washington Nationals. These divisional rivals are facing off as the regular season comes to an end, and both teams will be missing out on postseason play in 2025. Atlanta entered the season with far higher expectations, but a combination of poor play and injuries resulted in where they are right now. I do believe they hold the starting pitching edge in this matchup, however, with Hurston Waldrep taking the mound. He has a 2.78 ERA after 8 earned runs allowed in his last outing, which shows how dominant he was before that poor outing. Look for a bounce back effort in this spot.

Brad Lord is set to start this game for Washington, and he enters play with a 4.31 ERA. He has spent time in both a starting and relieving role this season, and while he is a serviceable option for this Nationals team, he is not a pitcher that strikes a ton of fear in opposing lineups. I look for the Braves to draw long counts against Lord and put up some crooked innings as they give Waldrep another shot at a win.

Atlanta Braves vs Washington Nationals prediction: Braves ML (-155) available at time of publishing. Playable at that price.

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Javan Shouey
6:45 PM ET
Yesterday
NESN
The Athletics
Boston Red Sox
Athletics
Red Sox
Run Line Pick
BOS Red Sox -1.5(+110)

I expect a multi-run win for the Boston Red Sox as they take on the Athletics Wednesday evening. Lucas Giolito is set to start this game for Boston, marking his 25th start of the season for his new club. The veteran right-hander has been a productive member of this rotation, providing the team with a 3.31 ERA across his 136 innings of work. He enters the game in good form with no more than 2 earned runs allowed in any of his last 4 outings. I expect a strong effort as he takes on an Athletics lineup that is worse when on the road.

Mason Barnett is set to start for the Athletics in this game. The right-hander has made 3 starts totaling 12.2 innings of work with an 8.53 ERA to show for it. His AAA numbers were not much better, and it is clear that his MLB promotion was out of a need for innings rather than a performance-based promotion. Boston is set up nicely for offensive success in this game, against both the starter and a shaky bullpen, and I look for a multi-run win in this one.

Boston Red Sox vs The Athletics prediction: Boston -1.5 (+110) available at time of publishing. Playable to +105.

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Javan Shouey

Vote on who will win!

7:10 PM ET
Yesterday
San Diego Padres
New York Mets
Padres
Mets
Money Line Pick
NY Mets Win(-125)

The San Diego Padres turn to veteran righty Nick Pivetta, who has quietly been their most reliable arm this season. Pivetta enters with a 13-5 record, 2.73 ERA, 0.95 WHIP, and 180 strikeouts across 171.1 innings, showing a strong ability to miss bats and limit baserunners. His mix of a firm fastball and sharp breaking pitches has kept most lineups off balance, though there are signs of regression as his hard hit rate and exit velocity against have ticked upward in recent starts. Against a disciplined lineup like the Mets, who can work counts and generate traffic, Pivetta may be tested more than usual. If New York can string together quality at bats early, it could open the door for run support before San Diego’s bullpen enters the picture.

The New York Mets counter with David Peterson, who has delivered a 9-5 record with a 3.77 ERA and 1.32 WHIP across 28 starts. While he’s had some uneven outings, Peterson has generally shown solid strikeout ability and improved command, allowing him to neutralize lineups when he finds his rhythm. His effectiveness comes from mixing a sinker/slider combination that keeps hitters off balance, and his recent outings have shown steadier results. Offensively, the Mets remain capable of taking advantage of mistakes, with their lineup producing timely power and extra base hits in key spots. Facing a tough starter in Pivetta won’t be easy, but with Peterson’s steadiness and the Mets’ ability to manufacture runs at home, the edge leans toward New York.

Padres vs Mets Prediction: Mets ML (-125) available at time of publishing. Playable to -135

Justin Ziolkowski
7:40 PM ET
Yesterday
AMZN, TWTV
New York Yankees
Minnesota Twins
Yankees
Twins
Money Line Pick
NY Yankees Win(-155)

With the playoffs inching closer, the New York Yankees will look to end their three-game series against the Twins on a high note. Taking the mound for New York will be Luis Gil who enters with a 4-1 record and a 2.83 ERA. Gil was fantastic in his last outing against the Red Sox, he didn’t allow a single hit or run through six innings. Over his last few starts, Gil has improved, but he still struggles to work deep into games, and with the Yankees bullpen looking shaky lately, that could be a concern heading into tonight’s matchup. 

Taking the mound for the Twins will be Taj Bradley who enters with a 6-7 record and a 4.88 ERA. Bradley is a familiar face for this Yankees lineup, and on the season, Bradley is 1-1 with a 6.75 ERA in 10.2 innings pitched against New York this year. Offensively, the Yankees have the edge in this matchup and they should have no issues on scoring runs against Bradley. Look for the Yankees to get the job done and remain the top seed in the AL Wild Card. 

Yankees vs Twins prediction: Yankees ML (-155) available at time of publishing. Playable at that number.

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Jason Fragomeni
8:10 PM ET
Yesterday
RSN, SCHN
Texas Rangers
Houston Astros
Rangers
Astros
Money Line Pick
TEX Rangers Win(-125)

In this game, we will see the Texas Rangers take on the Houston Astros. The season long series between these teams is currently tied 6-6. Today’s game will decide the winner. On the mound, we have Jacob deGrom of the Rangers and Christian Javier of the Astros. DeGrom is having a great season with a 2.82 ERA and a 12-7 record. His numbers have been slightly worse recently with him giving up 6 runs in his last 12.1 innings. What can provide some optimism is that the Astros lineup bats .212 against deGrom through 85 at-bats. Additionally, deGrom has pitched 5 or more innings in all but 1 start this season. This means they will not have toe strain the bullpen in this one. The Astros have also been held scoreless when the Rangers bullpen enters the game over the past 2 games. This means that deGrom just has to keep it close for the Rangers to have a chance.

For the Astros, Javier will take the mound. Javier has struggled in his recent starts giving up 3+ earned runs in 3 of his last 4 starts. He has also been pulled from the game prior to finishing the 5th inning in 3 of his last 5 starts. If Javier starts to struggle against a Rangers team that is batting .269 over the past 6 games, we may see many relief pitchers. The more relief pitchers that enter the game the higher chance that the Rangers put some runs on the board. I am rolling with the reliable deGrom and the hot bats of the Rangers. Rangers to win.

Rangers vs Astros prediction: Rangers ML (-125) available at time of publishing. Playable at that number.

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Mark H.
10:10 PM ET
Yesterday
MLBN, NSPA, SNLA
Philadelphia Phillies
Los Angeles Dodgers
Phillies
Dodgers
Money Line Pick
PHI Phillies Win(+125)

The Los Angeles Dodgers bullpen woes continued last night, giving up all 9 runs that the Phillies scored on Tuesday, which ultimately cost them the game. These two teams could very well meet again in the postseason, but there’s a lot of uncertainty surrounding the Dodgers and their bullpen. Tonight, the Dodgers will look to avoid being swept as they send Blake Snell to the mound, who enters with a 4-4 record and a 2.79 ERA. 

For the Phillies, Jesus Luzardo gets the nod, entering with a 14-6 record and a 4.03 ERA. While he’s had his ups and downs this season, he seems to have settled down, going 2-0 with a 2.61 ERA and 25 strikeouts in his last three games. As for Snell, he’s coming off one of his best starts of the season, but that was against the Rockies. The Phillies offense is surging right now, averaging 6.5 runs per game over their last 10 compared to the Dodgers 6.2. There’s a lot of value picking the Phillies tonight, and I believe they have the better pitcher and offense in tonight’s matchup. Look for the Phillies to complete the sweep, making them my best bet of the day. 

Phillies vs Dodgers prediction: Phillies ML (+125) available at time of publishing. Playable at that number.

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Jason Fragomeni
1:15 PM ET
Yesterday
Fanduel sports ohio
Cincinnati Reds
St. Louis Cardinals
Reds
Cardinals
Money Line Pick
CIN Reds Win(-120)

Wednesday’s matchup between the St. Louis Cardinals and Cincinnati Reds is an interesting one, and I lean towards a win for the Reds. Brady Singer and Andre Pallante are the scheduled starting pitchers for this game and there is a player prop bet that I like for both starters. Starting with Singer, the Reds’ right-hander has rounded into form over his last 9 starts, allowing just 13 earned runs in 53 innings during that span. That positive stretch has lowered his ERA nearly a full run, and his ability to work deep into games has been on full display as well, consistently covering his 17.5 outs recorded line.

Pallante is someone I am less confident in, and I am particularly concerned about his ability to throw strikes with consistency. He walked 4 Reds in their matchup just over 2 weeks ago and has been shaky with his command all season long, and today he has a playable 1.5 walks allowed prop. The Reds have shown decent plate discipline this season and they should also be able to damage with their bats. Look for the Reds to win this game.

Cincinnati Reds vs St. Louis Cardinals prediction: Reds ML (-120) available at time of publishing. Playable to -125 odds.

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Javan Shouey
3:40 PM ET
Yesterday
NBCSBA, ARID, MLBN
San Francisco Giants
Arizona Diamondbacks
Giants
Diamondbacks
Money Line Pick
SF Giants Win(-110)

The San Francisco Giants and Arizona Diamondbacks finish a series on Wednesday afternoon, and this series has become an unexpected battleground for the NL wild card. Both teams are trying to chase down the Mets, and the D-Backs have now climbed over both the Giants and Reds to put themselves in the hunt. For the Giants, Wednesday is awfully close to a do-or-die game, and I like them to salvage a win in the series after Arizona walked off a 6-5 win on Tuesday. My Giants vs Diamondbacks pick is the Giants on the money line.

For sure, I love the SF pitching situation far better. Justin Verlander has been terrific over his past 4 starts, thumbing his nose at Father Time while allowing only 3 runs in the past 24 innings. He is also backed by one of the league’s best bullpens when he leaves. Arizona will roll the dice with Brandon Pfaadt, and a roll of the dice it is with him every time out. Pfaadt has been blown up a ton of times this season, and only once in his last 4 starts has he escaped the 5th inning or allowed fewer than 4 runs. And whenever he leaves the game, he is followed by a D-Backs bullpen that has been a liability all season long. Arizona is clearly the superior lineup, but it is hard to look past this pitching advantage for the Giants. Give me SF to win.

Giants vs Diamondbacks prediction: Giants ML (-110) available at time of publishing. Playable at that number.

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Chad Hartsock
6:40 PM ET
Yesterday
CLEG, FDSNDT, FS1
Cleveland Guardians
Detroit Tigers
Guardians
Tigers
Game Totals Pick
Over 8.5(-110)

The Guardians and Tigers played an extra inning affair on Tuesday that resulted in a 7-5 Guardians win. Both teams burned through a lot of bullpen arms, as Cleveland used 6 different relievers and Detroit utilized four. With that in mind, it will be interesting to see who is available in each bullpen on Wednesday night. Detroit will send Jack Flaherty to the mound, and the 2025 season has not been kind to him. The veteran right-hander enters this contest with a 4.69 ERA over 151.2 innings of work this season. He is coming off a decent outing in which he tossed 5 scoreless innings against the Yankees, but given his season-long inconsistencies, it’s tough to expect that kind of performance in back-to-back starts.

Opposing Flaherty on the mound will be Cleveland left-hander Logan Allen. Like Flaherty, Allen has seen his fair share of struggles this season. He owns a 4.43 ERA through 144.1 innings this season. The Tigers have hit lefties well all season, and they enter this contest ranking second in the majors with a .788 OPS against southpaws. This could be another high-scoring affair. Look to the over on Wednesday.

Guardians vs Tigers prediction: Over 8.5 (-110) available at time of publishing. Playable to -115.

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Connor Grootenhuis

Vote on who will win!

7:05 PM ET
Yesterday
Sportsnet, FDSNSUN
Toronto Blue Jays
Tampa Bay Rays
Blue Jays
Rays
Money Line Pick
TOR Blue Jays Win(-130)

The Blue Jays have taken the first 2 games of this series by scores of 2-1 and 6-5. They now enter Wednesday’s matchup riding a riding a 6-game win streak. The Blue Jays have been one of the best teams in baseball since the All-Star break, and with the way they are rolling, it’s tough to go against them right now. It also helps that Kevin Gausman is slated to take the mound for Toronto. Gausman is coming off a complete game, 2-hit shutout against the Astros, and has allowed just 2 earned runs over his last 3 starts and 24 innings of work. Pitching on the road hasn’t phased him, as he is holding opponents to a measly .190 batting average away from Toronto. Look for the veteran right-hander to stay locked in against the Rays in this one.

The Rays appear to just be trying to get to the finish line at this point. Tampa Bay has fallen to 9 games back in the wild card, and has lost 9 of their last 11 games. Ian Seymour has been solid since transitioning to a starting role, but he has a tough assignment in this one going up against a Toronto offense that is doing plenty of damage right now. Back the Blue Jays on the road.

Blue Jays vs Rays prediction: Blue Jays ML (-130) available at time of publishing. Playable to -135.

Connor Grootenhuis
7:40 PM ET
Yesterday
FDSNW, FDSNWI
Los Angeles Angels
Milwaukee Brewers
Angels
Brewers
Run Line Pick
MIL Brewers -1.5(+110)

The Los Angeles Angels have dropped 5 straight games and scored 3 runs or fewer in each of their last 4 games. On Tuesday night, they suffered a 9-2 loss on the road against the Milwaukee Brewers, who have wins in 3 of their last 4 games. Unlike the Angels, the Brewers have been clicking offensively, scoring 8 or more runs in those 3 victories. Milwaukee enters Wednesday’s contest as significant favorites and I’m therefore making a play on the current run line. The Brewers rank inside the top 5 in both batting average and on base percentage against right-handed pitching, and they’ll be going up against Angels’ starter Jose Soriano.

Soriano owns a 4.13 ERA across 30 starts on the season, but he is coming off back-to-back starts that didn’t go in his favor. Soriano surrendered 8 earned runs and 5 walks against the Athletics on September 5 and walked 3 runners and allowed 3 earned runs across 4 innings in his latest start against the Mariners. The Brewers should be in position for some early success in this ballgame. Countering for the Brewers is right-hander Brandon Woodruff, who has looked good since returning from right shoulder surgery in July. Over 11 outings, Woodruff owns a 3.32 ERA and just tossed 6 scoreless innings with 8 punchouts in his latest start against the Pirates. The Brewers have the better lineup and the better starting pitcher on Wednesday night, so I’ll be backing them on the run line.

Los Angeles Angels vs Milwaukee Brewers Prediction: Brewers -1.5 (+110) available at time of publishing. Playable at that number.

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Kyle Lupas

Vote on who will win!

7:40 PM ET
Yesterday
RSNW, FDSNKC
Seattle Mariners
Kansas City Royals
Mariners
Royals
Money Line Pick
SEA Mariners Win(-105)

The Seattle Mariners face the Kansas City Royals again on Wednesday in the second of three games. The streaking Mariners have now won 10 games in a row, which has been enough to catapult them into the division lead, but only by half a game. They have done most of their damage with the bats, scoring in double digits in 4 of those 10 wins. With a showdown against the Astros looming this weekend, this is no time to relax. For the Royals, the story is the return of Cole Ragans. They had hoped to get Ragans back in time for a playoff push, but they have since faded well out of the race. A lot of sharp money is coming in on the Royals already today, but I am not interested in betting against this hot Mariners team. Give me the Seattle Money Line.

Ragans has not pitched in the Big Leagues since early June, missing 3 months with a shoulder injury. He will definitely be on a limited pitch count, and betting on immediate success after a long layoff is usually folly on our part. The Mariners will go with Bryce Miller, who is vulnerable, having given up 4 runs in 3 of his 5 starts since returning to the rotation. He did look better in his last outing though as he fanned 11 Angels (who are always good for one’s strikeout numbers). Even if Ragans is the more effective pitcher, he won’t be out there long, and I have a hard time betting against this Seattle offense right now, especially given the general struggles of the Royals on offense all season long anyway. I’ll keep riding with the Mariners.

Mariners vs Royals Prediction: Mariners ML (-105) available at the time of publishing. Playable at that number.

Chad Hartsock
8:40 PM ET
Yesterday
Miami Marlins
Colorado Rockies
Marlins
Rockies
Money Line Pick
MIA Marlins Win(-160)

The Miami Marlins will hand the ball to Ryan Weathers, who is coming off one of his best performances of the season after returning from injury. In his most recent outing, Weathers tossed five scoreless innings on just 68 pitches, allowing five hits, walking none, and striking out four. For the season, he owns a 2.73 ERA with a 1.04 WHIP, showing improved command and a knack for avoiding big innings. While his workload has been somewhat limited, his ability to keep traffic off the bases and consistently get ahead in counts has given Miami stability in a rotation that’s needed it. Against a Rockies lineup that has been inconsistent and often struggles to generate sustained rallies, Weathers’ approach could allow the Marlins to set the tone early.

The Colorado Rockies counter with rookie McCade Brown, who has endured a rough transition to the majors. In his first four starts, Brown has gone 0-4 with a 9.88 ERA and 2.12 WHIP, walking too many hitters and struggling to put away batters with consistency. His inability to work deep into games has exposed Colorado’s bullpen, often forcing them into action earlier than desired. While the Rockies have a few bats capable of making an impact at Coors Field, Brown’s lack of command has repeatedly put his team behind from the start. With Miami showing signs of life offensively and Weathers coming in with momentum, the Marlins appear better positioned on both the mound and at the plate.

 

Marlins vs Rockies Prediction: Marlins ML (-160) available at time of publishing. Playable to that number

Justin Ziolkowski

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There are 2,430 total games in the MLB regular season and our expert MLB picks provide insight and analysis including an MLB Expert Pick for all of the MLB games today, and be sure to head to our MLB Best Bets page for today’s top plays.

MLB Games Today – Today’s MLB Picks

We offer our MLB expert picks throughout the 6-month MLB season with great success. We have you covered with Today’s MLB Picks, available for all of the MLB games today. Our MLB picks cover the marquee matchups as well as the under-the-radar plays away from the spotlights where you often find tremendous value. Pitching matchups, weather, injuries, travel schedule, and many other factors are all taken into account to find the best MLB picks in all of the MLB games today.

2025 MLB Picks

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The most popular way to bet on MLB is via the Money line. This means games are basically handicapped based on each of the team’s starting pitchers. “Sure thing” pitchers such as Max Scherzer, Paul Skenes and Zack Wheeler are going to cost you, often requiring a $200 or more wager to make $100 (-200). Finding an even pitching matchup or one of those stud pitchers that may be fatigued and going against them is the best way to make money on the MLB. Our free MLB money line picks help you identify these profitable matchups throughout the baseball season.

MLB Picks Against The Spread – Run Line MLB Picks

The spread in baseball is known as ‘the run line’. Many bettors feel there isn’t as much value laying -200 on an all-star caliber pitcher because even elite pitchers can turn the game over to his bullpen who will subsequently blow the game and cost them the win. Therefore waging on the run line (-1.5 or +1.5) is a great way to find better MLB prices compared to the Money Line. A Zack Wheeler pick on the ML (win outright) for example might be -240 but betting that same game to win by 2 runs or more (run line) could be priced at -120. The MLB run line works in the opposite way too. There are a lot of 1-run games in baseball and betting on a team +1.5 runs is a great way to string together wagering wins if you think teams can keep games close.

Free Total Runs MLB Picks

There’s no other sport where the stadiums and the weather are so crucial to the scoring as the MLB. This is why our free MLB picks on the totals see almost as much wagering from the public as each side of the game itself.

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Our experts do all of this research and analysis for you and our accompanying game preview will detail all of the key factors in making our MLB Totals Picks for each game. 

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Free Baseball Picks Today

Baseball is a notoriously difficult sport to bet on day today. Teams will typically play each other in mini-series over a few days, and it’s common to see the sides split these games. Trying to find out which team is primed on any given day in a league built around parity is no easy task. To make the most informed decision about any matchup or wager requires a lot of time and research ahead of making our MLB baseball picks. Our expert handicappers will consider everything from pitching lineups, bullpen strength, the number of days on the road, player injuries, the stadium, the weather, and a whole host of advanced statistical models before making our baseball picks. With 2,340 regular-season games and up to 15 on any given day, that’s a lot of hours’ worth of research for any one person. That’s where we at Pickswise come to the fore. Our team of baseball, experts do the research for you. All of our baseball picks and free and come with full reasoning, analysis, and a confidence rating. Check out our MLB Best Bets page for our favorite plays today

What Is An MLB Computer Pick 

An MLB computer pick is an unbiased entirely stats-driven MLB pick  on the outcome of particular markets in a given MLB game.

Advanced stats, beyond the hits, runs and strikes, have long been associated with baseball, and the importance of it has grown immensely in recent years with regards to MLB picks and waging. With access to more and more data, we can use this information to find an edge in the MLB markets to bring you the best MLB picks from today’s games.

An MLB computer pick is generated by a supercomputer capable of simulating pre-game probabilities using advanced machine learning techniques by simulating each MLB game over 10,000 times to cater for the large range of outcomes and variables that can occur. It does this by running hundreds of algorithmic variabilities to predict the performance of each player, which is then used to run overall match simulations. This is then compared to the live odds and markets to find the biggest non-biased edges out there.

How To Use And Wager On MLB Computer Picks

There are many ways you can use MLB computer picks, with a wealth of information generated for various markets ahead of today’s MLB slate.

For each MLB game, you’ll find MLB computer picks for the Money line, Run Line, and Run Totals markets. You can also generate individual player projections with strikeouts, runs, & or hits, which are great for finding the edge on MLB player prop bets.

MLB Baseball Consensus Picks

MLB consensus picks are the picks in which the public are leaning and waging on any given MLB game, or market. For example, if 68% of the picks are on the Chicago White Sox money line, over the Detroit Tigers, then they are the consensus money line pick. However if 60% of the picks are on the Tigers ATS, then they are the consensus pick on the spread. The consensus, in short, is a way to gauge where the money is going, this can move lines and odds, so are worth keeping an eye on, at the very least, even if you intend on fading the public.

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