Arizona Diamondbacks vs Milwaukee Brewers Prediction, Odds and Picks for Today, 08/26/25

The Arizona Diamondbacks turn to Brandon Pfaadt, who has been serviceable yet inconsistent this season with a 12–8 record, 4.95 ERA, and 1.34 WHIP across 26 starts. His last outing showed his upside as he worked seven strong innings against Cleveland, allowing just two runs on five hits. Arizona’s lineup has the ability to support him with power, ranking third in the majors in slugging percentage (.438) and top five in home runs (183). Ketel Marte remains the anchor of the order, while Geraldo Perdomo and Corbin Carroll have added timely production. Still, this is a team that can be held in check when facing pitchers who attack the zone with confidence, as they rely heavily on extra base power rather than consistent contact.

For Milwaukee, Jacob Misiorowski gets the ball, a rookie who has already flashed electric potential. He carries a 4.19 ERA and 55 strikeouts in just under 40 innings, highlighted by a zero hit debut and six perfect innings in his second start. Though he’s shown some regression lately, Misiorowski’s velocity and swing and miss stuff give him the ability to navigate even power heavy lineups like Arizona’s. The Brewers’ offense has been opportunistic but not overpowering, leaning more on manufacturing runs than outslugging opponents. With Pfaadt capable of bouncing between quality starts and rocky outings, and Misiorowski showing both brilliance and growing pains, this matchup shapes up as one where the pitchers have a real chance to control the game. Given the balance of high strikeout potential against lineups that can be streaky, the best look is the under.

Dbacks vs Brewers Prediction: Under 8 (-105) available at time of publishing. Playable to that number