Arizona Diamondbacks vs Philadelphia Phillies Prediction, Odds and Picks for Today, 04/10/26

The Arizona Diamondbacks continue their East Coast road trip as they open a 3-game set against the Philadelphia Phillies. Arizona is coming off a series win over the Mets, taking 2 of 3, while the Phillies dropped 2 of 3 to the Giants and are still searching for offense after being held scoreless over their last 20 innings.

Taking the mound for the Diamondbacks will be Mike Soroka who is 2-0 with a 0.90 ERA through 2 starts this season. For the Phillies, they’ll send Jesus Luzardo to the mound who is 1-1 with a 4.97 ERA. Offensively, these teams have been very similar. The Phillies rank 20th in the league in OPS (.658) and average 3.5 runs per game, while the Diamondbacks rank 21st in OPS (.657) and average 4.3 runs per game. As far as the bullpen goes, the Diamondbacks bullpen has struggled this season, posting a 5.40 ERA while the Phillies hold a 3.89 ERA.

At the end of the day, both teams are fairly even offensively, and Soroka has been the stronger pitcher to start the season, but the real question is how will this Diamondbacks bullpen hold up if they get an early lead? Soroka hasn’t gone over 5 innings yet this season, and they’ll probably have to rely on Kevin Ginkel, Ryan Thompson, Juan Morillo, or Paul Sewald late in the game — who are well-rested. Despite the concerns surrounding their bullpen, I think the Diamondbacks are more than capable of keeping this game close. 

Diamondbacks vs Phillies prediction: Diamondbacks +1.5 (-135) available at time of publishing. Playable at that number.

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