Arizona Diamondbacks vs Philadelphia Phillies Prediction, Odds and Picks for Today, 04/12/26

The Phillies picked up a 4-3 win on Saturday against the Diamondbacks thanks to a pair of home runs from Kyle Schwarber and Bryce Harper, but they’ll have a tougher challenge on Sunday as they face Arizona’s ace. Zac Gallen enters this matchup with a 1-1 record and a 3.00 ERA through 3 starts this season. For the Phillies, they’ll send Andrew Painter to the mound, who is 1-0 with a 4.82 ERA as he looks to rebound from a tough outing in his last start — where he gave up 4 runs on 9 hits in 4 innings pitched against the Giants. 

The Diamondbacks have been one of the hotter hitting teams within the last week, and that could be troubling for Painter and the Phillies. Arizona is hitting .249 in their last 6 games, averaging 5.2 runs per game. As for the Phillies, they’ve been struggling offensively, hitting .191 and averaging just 2.5 runs per game in that same span. Despite the Phillies picking up a win on Saturday, I think this is going to be a tough spot for them to get things going against Gallen. Gallen has been dominant in his last 2 starts, allowing just 1 earned run and striking out 7 in his last 11 innings. Look for the Diamondbacks to get things done on the road and secure a series win. 

Diamondbacks vs Phillies prediction: Arizona Diamondbacks ML (+120) available at time of publishing. Playable at that number.

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