Baltimore Orioles vs New York Yankees Prediction, Odds and Picks for Today, 09/26/25

Tied for first place in the AL East, the New York Yankees welcome the Baltimore Orioles for the final three-game series of the regular season. The Yankees did their job against the White Sox, completing the sweep. Baltimore, on the other hand, took two out of three against the Rays, as they look to get out of the cellar in the AL East and will now try to play spoiler heading into this series against New York. 

Taking the mound for the Orioles will be Trevor Rogers who enters with a 9-2 record and a 1.35 ERA. In his last start, Rogers picked up the win against the Yankees, throwing six scoreless innings while allowing just one hit and striking out seven. The Yankees will counter with Will Warren, who enters with a 8-8 record and a 4.35 ERA. Warren pitched well against Baltimore in his last start, allowing only one run on four hits, though he was tagged with the loss. This will be a classic division-rival rematch, however, if the Yankees want to make a run this postseason, they’ll need to find a way to beat good pitching – and I think they’ll do just that against Rogers tonight. 

Orioles vs Yankees prediction: New York Yankees (-150) available at time of publishing. Playable at that number.

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