Baltimore Orioles vs Pittsburgh Pirates Prediction, Odds and Picks for Today, 04/05/26

The Pittsburgh Pirates and Baltimore Orioles finish a series on Sunday afternoon. The Pirates are looking for the sweep after mounting a late-inning comeback on Saturday, pushing their winning streak to 4 games in a row. The Orioles, on the other hand, seem to have some significant issues in the early stages of the season. I am looking for the Pirates to close out the series with a win, and I am taking the Pirates on the Money Line.

Chris Bassitt takes the ball for the Birds. I have concerns about Bassitt at this stage of his career, but the Orioles are hoping to milk one more season out of the 37-year old. His first start was a rough one, but more concerning to me is that the heart of the Pittsburgh batting order have all logged 15+ at-bats against Bassitt, and found a lot of success. Lowe, Reynolds, and O’Hearn are collectively just under .500 against Bassitt. That could be trouble. For the Buccos, it will be Braxton Ashcraft taking the ball. This is a young and promising arm who is still learning on the job. He is far from a finished product, but the Oriole offense is a mess through the first two weeks. On top of that, the bullpen just blew a save, so the Pirates likely have a late-inning bullpen advantage on Sunday. This one should break the direction of the home team as they raise the Jolly Roger.

Orioles vs Pirates Prediction: Pittsburgh Pirates ML (-130) available at the time of publishing. Playable at that number.

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