Baltimore Orioles vs San Francisco Giants Prediction, Odds and Picks for Today, 08/29/25

The Baltimore Orioles send right hander Dean Kremer to the mound, and he’s starting to show encouraging signs after a rough start to his season. Kremer was knocked around early, including a game where he gave up 8 extra base hits, but he’s bounced back with consecutive strong outings. Over his last 2 starts, he’s allowed just 4 total earned runs across 13 innings while striking out 8 and limiting opponents to soft contact. His ERA still sits in the mid-4s, but the sharper command and improved pitch sequencing have helped stabilize Baltimore’s rotation. Supported by a defense that has been one of the more reliable units in the American League, Kremer doesn’t need to dominate to give his team a real shot, and if he keeps suppressing hard contact, the Orioles should be in good position to compete.

The San Francisco Giants will counter with lefty Robbie Ray, who has been the unquestioned anchor of their rotation. Ray enters with a 2.93 ERA and 1.12 WHIP across 159 innings, combining strikeout ability with veteran poise. He’s been in command for much of the season, stringing together one of the longest winning stretches by a Giants starter in recent years. That said, he still has occasional issues with the long ball, and the Orioles’ lineup—featuring multiple right-handed bats capable of driving the ball—could test him in a way recent opponents haven’t.

While Ray may give the Giants a slight edge on paper, the Orioles’ improving lineup and Kremer’s upward trend provide a strong case for an upset. Baltimore’s ability to grind out ABs and capitalize on mistakes, paired with San Francisco’s at times inconsistent offense, makes this matchup more even than the numbers suggest. With that in mind, the lean is toward the Orioles Money Line, as Kremer and Baltimore’s bats are capable of doing just enough to edge out Ray and the Giants.

Orioles vs Giants prediction: Orioles ML (+125) available at time of publishing. Playable to +100.

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