Chicago Cubs vs Pittsburgh Pirates Prediction, Odds and Picks for Today, 04/29/25
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Cubs vs Pirates Pickswise Expert Predictions
It’s an NL Central showdown as the Chicago Cubs head east to take on the Pittsburgh Pirates. Both teams are coming off back-to-back losses and will look to regain momentum heading into the month of May. This will be the first time the Cubs have faced anyone from their own division and it should be an exciting matchup as these two clubs are playing at completely different levels this season. It’s going to be a southpaw battle as the Cubs are expected to start Shota Imanaga who’s 2-1 with a 3.18 ERA in six starts this season. Imanaga has struck out 27 and has a WHIP of 1.09 in 34 innings. For the Pirates, Andrew Heaney has been having himself a year. The 11th-year veteran is 2-1 with a 1.72 ERA in five starts. In 31.1 innings pitched, Heaney has struck out 31 and has a WHIP of 0.77.
Heany has been impressive this season, there’s no denying that, but the last time he faced an offense as powerful as the Cubs were the Yankees back on April 6. The Cubs love hitting left-handed pitching, batting .282 with 11 homers. It doesn’t matter who the Pirates face, their offense is one of the worst in all of baseball, sitting in 27th in OPS (.645) and averaging just 3.5 runs per game. As for the Cubs, they’re first in all of baseball in OPS (.784) and average 5.9 runs per game. Heany is going to have his work cut out for him and at the end of the day, this Cubs team is more well-rounded than the Pirates, which is why I’ll be backing the Cubs moneyline as my best bet of the day.
Cubs vs Pirates prediction: Chicago ML (-155) available at time of publishing. Playable at that price.
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Jason Fragomeni
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The Cubs have won 4 of 5 games at divisional opponents.
The Cubs have failed to cover the run line in 3 straight road games.
The Under is 4-1 in the Cubs' last 5 matchups against divisional opponents.
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