Cincinnati Reds vs St. Louis Cardinals Prediction, Odds and Picks for Today, 09/16/25
Reds vs Cardinals Pickswise Expert Predictions
In this game, we will see the Cincinnati Reds take on the St. Louis Cardinals. The Reds won last night’s game by a score of 11-6. On the mound today, we have Andrew Abbott of the Reds and Michael McGreevy of the Cardinals. Abbott started the season in amazing form and has since come back to life. Even with some struggles, he has a 2.79 ERA with a 9-6 record. In his most recent start, he pitched 8 innings against the San Diego Padres and only gave up 5 hits and 1 earned run. These are the starts that we are expecting out of Abbott this year. Abbott will face a Cardinals lineup that rank 17th in batting average, 17th in hits, and 18th in runs scored this season. Abbott has also faced the Cardinals 3 times this season where he has pitched 16 innings while giving up 10 hits and 3 earned runs. I suspect he will have similar success again today with the momentum from his last start.
For the Cardinals, McGreevy will take the mound. McGreevy has a 4.44 ERA and a 6-3 record on the season. The issue is that McGreevy has struggled at home. In his home starts, he has a 6.07 ERA while giving up 13 runs in his last 16 innings. He has also given up 5 home runs through those starts. These numbers are concerning when going up against a motivated Reds lineup that is batting .246 on the season and rank 13th in runs scored. Outside of the starters, the Cardinals bullpen has been better on the season, but has given up 17 earned runs over the last 5 games. Given the Reds are only 2 games out of the wild card with Abbott on the mound, I am taking the Reds to get the win.
Reds vs. Cardinals Prediction: Reds ML (-120) available at the time of publishing. Playable at that number.
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