Cleveland Guardians vs Chicago Cubs Prediction, Odds and Picks for Thursday, 07/03/25

In this game, we will see the Cleveland Guardians face off against the Chicago Cubs. The Cubs have won the previous 2 games against the Guardians by scores of 5-2 and 5-4. For today, the starting pitchers will be Luis Ortiz of the Guardians and Cade Horton of the Cubs. Ortiz has been very up and down this season. Over his last 5 games, he has had 2 games where he gave up 0 earned runs and 3 games where he has given up 4+ earned runs. It is hard to tell which version of Ortiz we will get in this game. One thing that is certain for this game is that the Cubs are hitting the ball well. They are batting .276 over the past 6 games while accruing 56 hits and 29 runs. On the season, the Cubs rank 2nd in runs scored and 2nd in hits. Even if the best version of Ortiz shows up, I suspect that this Cubs lineup will be able to put up some runs.

For Chicago, Horton will get the start. Horton has struggled in his last 2 games, giving up 15 hits and 10 earned runs in just 8.2 innings. Luckily for the Cubs, these games were against 2 teams that have been hitting the ball very well. Cleveland comes into this game ranked 29th in batting average, 27th in runs scored, and 30th in hits. Additionally, the Guardians are batting .145 over the past 6 games and have only scored 12 runs in that time. Overall, I believe that the Guardians’ inability to score runs will be their downfall here. Ortiz may pitch well, but the Guardians’ bullpen is significantly worse than the Cubs’ bullpen. I suspect that the Cubs will put up some runs and the Guardians will struggle to keep it close. I am taking Chicago to make it 3 in a row.

Guardians vs Cubs prediction: Cubs ML (-155) available at time of publishing. Playable at that number.

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