Detroit Tigers vs Arizona Diamondbacks Prediction, Odds and Picks for Today, 03/31/26

The Arizona Diamondbacks host the Detroit Tigers on Tuesday after taking the first game in the series on Monday. The first game was a weird one, with Arizona jumping out to an early lead behind a strong debut by Mike Soroka, and then the bullpen nearly gave it all back. On Tuesday, we get two of the better, even if volatile, back-of-the-rotation arms in Casey Mize and Brandon Pfaadt. It is never a fun night backing Pfaadt, but I do like the Diamondbacks here as they continue to look to recover from their season-opening sweep by the Dodgers.

Pfaadt always seems to have that one bad inning that wrecks his start, but for what it is worth, he has looked fantastic in the preseason. There is so much potential here, if he ever harnesses it. Mize, on the other hand, was a mess in his final spring start, and he voiced that his mechanics were off. Do we trust him to have it fixed immediately? Both teams have strong lefty bats, so this game could see some scoring, but I am going to trust the D-Backs side of that platoon and hope that we get good Pfaadt for a few starts to open the season.

Tigers vs Diamondbacks prediction: Diamondbacks ML (-115) available at time of publishing. Playable at that number.