Detroit Tigers vs Miami Marlins Prediction, Odds and Picks for Today, 09/12/25

The Tigers head to Miami after taking 2 of 3 from the Yankees earlier this week. Detroit dominated the first 2 games of the series by a combined score of 23-3 before falling in the series finale. Looking to get back in the win column, the Tigers are happy to send Tarik Skubal to the mound on Friday night. The reigning Cy Young winner is dialed in right now. Skubal has allowed just 1 earned run over his last 4 starts and 27.2 innings of work. The Tigers have won 6 of his last 7 starts, and Skubal owns a microscopic 2.02 ERA and .192 BAA when pitching on the road this season. With the way he is rolling right now, the Marlins have a tough assignment on their hands.

Miami’s Sandy Alcantara will oppose Skubal on the mound. It’s been an up-and-down season for the veteran right-hander, and while he’s been better in recent weeks, he’s still hard to trust. The Marlins have won just 2 of his last 7 starts, and he could have his hands full with a well-rounded Tigers lineup that is coming off a great series in New York. With Skubal on the mound, look for the Tigers to take control of this contest. Back Detroit on the run line in this one.

Tigers vs Marlins prediction: Tigers -1.5 (-115) available at time of publishing. Playable to -120.

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