Detroit Tigers vs New York Yankees Prediction, Odds and Picks for Today, 09/11/25

The Detroit Tigers turn to left hander Tyler Holton, who has transitioned from the bullpen into a valuable multi-inning option this season. With a 3.80 ERA, 1.12 WHIP, and 55 strikeouts across 68.2 innings, Holton has proven effective at limiting baserunners and keeping games under control. His strength lies in navigating lineups the first time through, where he’s consistently kept hard contact to a minimum. That plays well against a Yankees lineup that has been inconsistent and prone to strikeouts. While Detroit’s offense hasn’t always been reliable, it has shown enough pop to support a steady outing from Holton, especially if he can keep the game close early. Something to note is that Holton could just be used in an opener type role, luckily, the Tigers have a solid bullpen.

For the New York Yankees, rookie Cam Schlittler gets the ball, carrying a 3.24 ERA and 1.34 WHIP through 10 big-league starts. He’s shown flashes of potential, with solid strikeout stuff and poise on the mound, but he’s also run into trouble when his command falters. A recent start against Toronto saw him surrender 4 runs in just 1.2 innings, highlighting some of the volatility that comes with young pitchers. While the Yankees’ offense has enough firepower to capitalize on mistakes, their inconsistency has left the door open in games like this. With the Tigers hot streak on one side and Schlittler’s risk of regression on the other, the edge tilts toward Detroit.

Tigers vs Yankees Prediction: Tigers ML (+125) available at time of publishing. Playable to any number.

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