Houston Astros vs The Athletics Prediction, Odds and Picks for Today, 04/05/26

The Houston Astros will take on the Athletics Sunday. This will be the 3rd leg of the series with both teams winning one so far. On the mound will be Lance McCullers Jr. of the Astros and Jacob Lopez of the Athletics. McCullers looked great in his first start, going 7 innings against the Boston Red Sox while only giving up 4 hits and 1 run. The Astros will be hopeful he can match this performance. On the season, the Astros are batting .259 with 69 hits and 49 runs. These are great hitting statistics.

For the Athletics, Lopez will get the start. Lopez pitched only 4 innings in his first start giving up 6 hits and 3 runs to the Atlanta Braves. This could be bad news with how well the Astros are hitting the ball. Looking at the Athletics, they are batting .206 with only 28 runs this season. These hitting struggles have made it that the Athletics have scored 2 or fewer runs in 5 of their 8 games this season. Additionally, the Athletics bullpen has been struggling and has given up 9 runs over the past 2 games against the Astros. I am rolling with the Astros on the money line.

Astros vs. Athletics Prediction: Houston Astros ML (-125) available at the time of publishing. Playable at that number.

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