Kansas City Royals vs Los Angeles Angels Prediction, Odds and Picks for Today, 09/25/25

The Kansas City Royals and Los Angeles Angels are both eliminated from playoff contention, figuratively limping to the finish line to wrap up the 2025 season. Michael Lorenzen (4.70 ERA, 1.35 WHIP) takes the bump for KC while 24-year-old call-up Mitch Farris (6.52 ERA, 1.45 WHIP) gets the start for L.A. The fact of the matter is Lorenzen has been unreliable all season, while Farris has surrendered 11 earned runs in his last 8.1 innings pitched. Both offenses enter this one on their weaker split, as KC is worse off against LHP like Farris while L.A. has struggled against RHP in 2025. However, the Royals have been hitting the ball well recently.

Over the last 14 days, Kansas City ranks 5th in both wRC+ and wOBA. Meanwhile, the Angels rank 28th and 29th in the same categories, respectively. Kansas City has a significantly better bullpen unit in relief, and I’ll back the Royals to get the win on the road in this somewhat meaningless spot for both teams.

Royals vs Angels prediction: Kansas City Royals ML (-110) available at time of publishing. Playable at that number or better.

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