Los Angeles Angels vs Milwaukee Brewers Prediction, Odds and Picks for Today, 09/18/25

The Angels are in the middle of a 10-game road trip, and it is not going well so far. Los Angeles has dropped the first six games of the trip, which includes the first two games in this series against the Milwaukee by a combined score of 18-4. Things won’t get any easier for the Angles in the series finale as they are set to go up against Milwaukee starting pitcher Quinn Priester. The Brewers tend to win games when he pitches. Milwaukee has reeled off wins in 18 straight games started by the 25-year-old right-hander. He’s consistently put his team in a position to win, which has his record sitting at 13-2 on the season.

Los Angeles started Yusei Kikuchi owns a less-than-ideal 8.56 ERA through 3 starts in September. He’s also really struggled on the road this season. Kikuchi’s ERA jumps from a solid 3.00 at home to 5.16 on the road. In addition, his BAA goes from .252 at home to .282 when pitching away from Los Angeles. The Brewers are closing out the regulars season as one of the top teams in baseball, while the Angels are just trying to get through the season. Fade Los Angeles and back Milwaukee at home in this one.

Angels vs Brewers prediction: Milwaukee Brewers ML (-190) available at time of publishing. Playable to -195.

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