Los Angeles Dodgers vs Baltimore Orioles Prediction, Odds and Picks for Today, 09/06/25

The Orioles defeated the Dodgers by a score of 2-1 in the series opener on Friday night. Saturday’s contest could yield another low-scoring affair. Baltimore’s Trevor Rogers is on a sensational run right now. After missing April and most of May, Rogers has posted an excellent 1.39 ERA and 0.82 WHIP over 90.1 innings this season. He has allowed exactly 1 earned run in 6 August starts that spanned 42 innings. He’s also been extremely accurate, racking up 41 strikeouts and walking just six in August. The Los Angeles offense has struggled in recent weeks, and Rogers should be able to keep things rolling in this one.

The Dodgers will send Yoshinobu Yamamoto to the mound. He is holding his opponents to a measly .187 batting average when pitching on the road, and Baltimore’s offense has not been very consistent this season. Yamamoto is coming off an outing in which he tossed 7 shutout innings against the Diamondbacks with 10 strikeouts and no walks. That should give him plenty of confidence going into this matchup. With a strong pitching matchup like this, look to the under.

Dodgers vs Orioles prediction: Under 8.5 (-120) available at time of publishing. Playable to -125.