Los Angeles Dodgers vs San Francisco Giants Prediction, Odds and Picks for Today, 09/13/25

The Los Angeles Dodgers will look to shake things off after suffering a tough 5-1 loss to the Giants last night, capped off by a walk-off grand slam in the bottom of the 10th. Taking the mound for the Dodgers will be the left-hander Clayton Kershaw who enters with a 10-2 record and a 3.27 ERA. Kershaw has been sharp as of late and his last loss goes all the way back to July 26th. Since then, he’s 6-0 with a 2.75 ERA. 

For the Giants, they’ll counter with Logan Webb who enters with a 14-9 record and a 3.12 ERA. Webb also has been dealing with his last loss going back to August 11th, and since then, he’s 4-0 with a 2.03 ERA. The one thing that scares me right now about this Dodgers team is their ability to produce runs. In their last 10 games, they’re averaging 3.9 runs per game compared to the Giants 6.2. Both pitchers have been fantastic, and I think this game will be decided by the bullpen. However, given the Dodgers recent struggles and with the Giants heating up, I’m leaning towards San Francisco to get the job done tonight.

Dodgers vs Giants prediction: Giants ML (+105) available at time of publishing. Playable at that number.