Minnesota Twins vs Baltimore Orioles Prediction, Odds and Picks for Today, 03/26/26

Joe Ryan is quietly one of the more reliable starters in the American League, and backing him as a plus-money underdog is the type of spot bettors should be circling. Ryan’s profile is exactly what you want early in the season: consistent command, low traffic, and the ability to work efficiently. Last year, he posted 13 wins, a mid-3.00 ERA and a sharp 1.04 WHIP. These metrics highlight a pitcher that limits damage and keeps his team in every game. That stability plays well in an Opening Day environment where volatility is already high.

Baltimore, on the other hand, comes in with underlying concerns that the market seems to be overlooking. Their bullpen was among the worst in baseball last season, and that’s not a flaw that gets fixed overnight. Meanwhile, their offense can be feast-or-famine. The O’s are dangerous when the long ball is there, but prone to disappearing when it’s not. Adding Pete Alonso doesn’t change the dynamics, it just makes their long-ball potential greater. With the better starting pitcher, more serviceable bullpen, and plus-money attached to the former, this is a clear value play. It’s Twins or pass.

Twins vs Orioles prediction: Minnesota Twins ML (+125) available at time of publishing. Playable at that number.