New York Mets vs St. Louis Cardinals Prediction, Odds and Picks for Today, 03/31/26

The New York Mets picked up a 4-2 win over the St. Louis Cardinals last night and will look to keep the momentum going as they send Kodai Senga to the mound. Senga went 7-6 with a 3.02 ERA last season and looked sharp this spring, striking out 11, allowing six hits and two earned runs in 9.2 innings pitched. For the Cardinals, they’ll counter with Andre Pallante who struggled last season, posting a 6-15 record and a 5.31 ERA, however, he did look solid in spring training, striking out 11 and giving up just four earned runs in 14 innings pitched.

Both offenses have started the season well, with St. Louis ranked 11th in OPS (.747) and the Mets sitting 10th (.751) through their first four games. However, the difference in this matchup comes on the pitching side. The Mets have been excellent on the mound, posting a 2.77 team ERA, backed by a bullpen that holds a strong 2.00 ERA. For the Cardinals, they’ve struggled significantly, carrying a 6.32 team ERA, with their bullpen being a major issue with a 7.94 ERA, which puts them near the bottom of the league. Offensively, Luis Robert, Juan Soto, and Francisco Alvarez have helped lead the way early for New York. As for St. Louis, they have Alec Burleson who is batting .400, Victor Scott and Jordan Walker hitting .385 in their first four games, but this is a much tougher matchup for them against a solid Mets pitching staff. Even on the road, the Mets hold the edge in both starting pitching and bullpen reliability. With Pallante still a question mark and the Cardinals’ bullpen struggling, New York is in a strong position to take control of this game early on tonight against the Cardinals.

Mets vs Cardinals prediction: Mets ML (-165) available at time of publishing. Playable at that number.