New York Yankees vs Baltimore Orioles Prediction, Odds and Picks for Today, 09/18/25

With just a two-game lead in the AL Wild Card standings, the New York Yankees will open a four-game series against the Baltimore Orioles. This is a pivotal series for the Yankees, and it’s a series they can’t afford to lose. The Orioles have managed to win six of their last ten games, but offensively, they’ve struggled averaging just 3.2 runs per game in that span. 

New York will send Max Fried to the mound, entering with a 17-5 record and a 3.03 ERA. The left-hander has won four in a row and holds a 2.39 ERA in that span. For the Orioles, Cade Povich will get the start, entering with a 3-7 record and a 5.05 ERA. The Yankees offense has been doing its part, averaging 4.9 runs per game, but their pitching staff has struggled with a 5.93 ERA in that span. Even so, Fried has clearly found his groove, and Povich has struggled all season. New York has been the better team all season and they should be able to take care of business against their division rival. 

Yankees vs Orioles prediction: New York Yankees -1.5 (-125) available at time of publishing. Playable at that number.

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