New York Yankees vs Boston Red Sox Prediction, Odds and Picks for Today, 09/13/25

The New York Yankees and Boston Red Sox square off in game 2 of this pivotal 3-game series, with both teams hoping to inch closer to the Blue Jays in the standings. Brayan Bello will get the start for Boston, entering with a 11-6 record and a 3.12 ERA. His biggest challenge tonight will be slowing down Aaron Judge, who has been on fire lately — batting .385 with four home runs and six RBIs in his last 4 games. If the Red Sox want to win, they’ll need to find ways to cool him off at the plate.

For the Yankees, Max Fried gets the start. He is 16-5 with a 3.02 ERA. Fried will be looking for his fourth straight win, and in his last 3 starts he is 3-0 with a 2.14 ERA. Both pitchers have been dominant against their opponents this season. Bello is 2-0 with a 0.00 ERA in 2 starts against the Yankees. Fried is 0-1 with a 1.38 ERA in that same span against the Red Sox. As I expect this to be a pitching duel, I’m leaning toward New York in this one. Judge plays a huge role in this Yankees offense, and if they try to walk him to prevent him from hitting a homer, you’ll most likely have to face Cody Bellinger and Giancarlo Stanton — and both are never easy outs. Look for New York to cruise.

Yankees vs Red Sox prediction: New York ML (-135) available at time of publishing. Playable at that number.

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