Pittsburgh Pirates vs Milwaukee Brewers Prediction, Odds and Picks for Today, 06/23/25

The Pirates and Brewers are set to begin a 3-game series at American Family Field on Monday night. The Brewers enter the new week playing solid baseball. They are currently riding a 4-game win streak and have found the win column in 8 of their last 11 games. The Milwaukee offense is a big reason for their recent success, as they’ve plated 43 total runs during their 4-game win streak. The offense is rolling right now, and Pittsburgh’s Braxton Ashcraft could have his hands full on the mound. Ashcraft will start the night toeing the rubber but several relievers could see action as well.

The Pirates are just 11-27 on the road so far in 2025, and their .598 OPS in road games is dead last in all of baseball. Milwaukee’s Chad Patrick has been far better at home during his rookie campaign. His ERA goes from 4.40 on the road to 2.93 at home, and his BAA goes from .283 to .228. With the way Milwaukee is rolling right now, it’s hard to go against them in this spot, especially on their home field against a Pirates team that has struggled away from Pittsburgh all season long. Let’s go with the Brewers to win this one comfortably.

Pirates vs Brewers prediction: Brewers -1.5 (-105) available at time of publishing. Playable to -110.

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