San Francisco Giants vs San Diego Padres Prediction, Odds and Picks for Tuesday, 04/29/25
Vote on who will win!
Giants vs Padres Pickswise Expert Predictions
The San Francisco Giants and San Diego Padres open a quick 2-game series at Petco Park on Tuesday night. These National League West rivals have each started out the season well, with the Giants going 19-10 overall — including an impressive 10-6 record on the road. They are dead even with the Los Angeles Dodgers for first place, and surprisingly it’s the Giants who lead in the NL West with a plus-28 run differential. The Padres lurk not far behind at 17-11, although they have tailed off somewhat after a blistering hot start — especially at home. The Padres are still a very respectable 12-4 at Petco Park, but they have lost 4 of the past 5 games at home — including a stunning, low-scoring 3-game sweep at the hands of the Tampa Bay Rays.
The under has cashed in 5 straight games for San Diego, as the offense has managed 2 or fewer runs in 5 in a row. The under is 5-0 in the past 5 at home, too, while going 7-1 across the past 8 overall. Things don’t figure to get much better against Giants RHP Logan Webb, who trots in with an impressive 1.98 ERA, 1.10 WHIP and 44 strikeouts across 36.1 innings in his 6 outings. The red-hot Nick Pivetta of San Diego isn’t likely to give up much, either. He has a sparkling 1.20 ERA and 0.77 WHIP across 30.0 innings in 5 starts. This should be an amazing pitchers’ duel.
Under 6.5 (-110) at time of publishing. Playable to -120.
Joe Williams
The Padres have won 3 straight matchups against divisional opponents.
The Padres have failed to cover the run line in 7 of their last 9 games.
9 of the Padres' last 11 home games stayed Under the total.
$500
Get A $500 No Sweat First Bet On The Kentucky Derby
For NEW users only
Make your first deposit and it will be matched it up to $500
Users can claim these via promos tab or banner
For NEW users only. New users will receive a 100% match on their deposit, up to $500. Users can claim these via promos tab or banner.
$500
Get A $500 No Sweat First Bet On The Kentucky Derby
For NEW users only
Make your first deposit and it will be matched it up to $500
Users can claim these via promos tab or banner
For NEW users only. New users will receive a 100% match on their deposit, up to $500. Users can claim these via promos tab or banner.
$250
Bet $50, Get $250 In Bonus Bets
Sign up for a new Fanatics Sportsbook account.
Bet $10 on any event for 5 straight days
You\'ll get $50 in bonuses each day ($250 total)
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
$250
Bet $50, Get $250 in Bonus Bets
Sign up for a new Fanatics Sportsbook account.
Bet $10 on any event for 5 straight days
Each days, you'll get $50 in bonuses ($250 total)
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
$250
Bet $50, Get $250 in Bonus Bets
Sign up for a new Fanatics Sportsbook account.
Bet $10 on any event for 5 straight days
Each day, you'll win $50 in Bonus Bets ($250 total)
Must be 21+ to participate. | T&Cs apply. | Play Responsibly. | Gambling problem? Call 1-800-522-4700; AZ 1-800-NEXT-STEP; CT (888) 789-7777; MA (800)-327-5050; NY 877-8-HOPENY or text HOPENY (467369); VA 1-888-532-3500; CO, IA, KS, KY, MD, NJ, OH, PA, TN, VT, WV 1-800-GAMBLER; MD Please play responsibly, for help visit mdgamblinghelp.org or call 1-800-GAMBLER
3,600
1.1 Million Gold Coins + FREE 3,600 Sweeps Coins
Sign up for a new Funrize account
You\'ll get 1.1 million gold coins + 3,600 sweeps coins for just $19.99
Terms and Conditions apply. 18+ to play.
3,600
1.1 Million Gold Coins + FREE 3,600 Sweeps Coins
Sign up for a new Funrize account
You'll get 1.1 million gold coins + 3,600 sweeps coins for just $19.99
Terms and Conditions apply. 18+ to play.
$200
Bet $5, Get $200 Instantly!
Sign up for a new account with DraftKings Sportsbook and make your first deposit
Bet $5 on any sports market and get $200 instantly
Gambling Problem? Call 877-8-HOPENY/text HOPENY (467369) (NY), If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (CO/IL/IN/LA/MD/MI/NJ/PA/TN/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (KS), 888-789-7777/visit ccpg.org (CT), 1-800-BETS OFF (IA), or 1-888-532-3500 (VA). 21+ (18+ WY). Physically present in AZ/CO/CT/IL/IN/IA/KS/LA(select parishes)/MD/MI/NJ/NY/PA/TN/VA/WV/WY only. Void in OH/ONT. Eligibility restrictions apply. Valid 1 per new customer. Min. $5 deposit. Min. $5 bet. $200 issued as bonus bets that expire 7 days (168 hours) after being awarded. See terms at sportsbook.draftkings.com.
$200
Bet $5, Get $200 Instantly!
Sign up for a new account with DraftKings Sportsbook and make your first deposit
Bet $5 on any sports market and get $200 in bonus bets instantly
Must be 21+. Gambling Problem? If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537). See terms at sportsbook.draftkings.com.
Coins
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Sign up for an account with Sportzino
You’ll get a 1,570,000 Gold Coins + 45 free Sweeps Coins upon signup
Start making bets with the at the Sportzino Social Sportsbook & Casino
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Coins
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
Sign up for an account with Sportzino
You’ll get a 1,570,000 Gold Coins + 45 free Sweeps Coins upon signup
Start making bets with the at the Sportzino Social Sportsbook & Casino
Get up to 1,570,000 Gold Coins + 45 FREE Sweeps Coins upon signup
COINS
Sign up to get 15,000 Gold Coins + 2.5 free Sweepstakes Coins
Sign up for a new Hello Millions casino account
Sign up to get 15,000 Gold Coins + 2.5 free Sweepstakes Coins
First-purchase bonus: 230,000 GC + 115 SC for $69.97 over first three purchases
Available to players aged 18 and up only. Gambling problem? Call 1-800-GAMBLER.
MLB Video
MLB Analysis
See All MLB News
MLB Picks & Predictions for Tuesday, April 29: Giants vs Padres & Marlins vs Dodgers Best Bets
The 2025 MLB season keeps rolling along, and Tuesday features a full slate of games for us to enjoy. I'm 10-2 on my MLB best bets and the Pickswise MLB handicapping team as a whole is 30-11-3 on thei...
