San Francisco Giants vs San Diego Padres Prediction, Odds and Picks for Wednesday, 04/30/25
Mark Hamilton
The Padres have won 4 of their last 5 games at home against divisional opponents.
The Giants have failed to cover the run line in 6 of their last 7 road games.
Each of the Padres' last 3 home games against the Giants have gone Over the total.
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