St. Louis Cardinals vs Washington Nationals Prediction, Odds and Picks for Today, 04/06/26

The Washington Nationals and St. Louis Cardinals open a series on Monday in the nation’s capital. The schedule makers were mean to the Nats to start the season, sending them to the Cubs to open ad then hitting them with Philly and the Dodgers. It is no surprise that the Nats have lost 5 in a row now, although they were ahead of the Dodgers a couple of times and didn’t play all that poorly. The Cardinals took the Sunday night game from Detroit to salvage 1 game in that series. Of course, we also know that the game following Sunday Night Baseball is traditionally a letdown spot for teams. As such, I’ll take the Nationals on the money line.

The pitching matchup is rather unexciting, as Andre Pallente faces Zack Littell. Pallente is a ground-ball machine who doesn’t miss many bats, and Littell is a back of the rotation arm that worked behind an opener in his first start. Both bullpens have been a liability so far this season, too. The difference in this game for me is all the lefties that Washington can stack in the lineup. This team is not bad — and on days when the Nats face right-handed pitching, they can be a real problem. I’ll take Washington at home.

Cardinals vs Nationals prediction: Washington ML (+100) available at time of publishing. Playable at that number.

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