Tampa Bay Rays vs Chicago White Sox Prediction, Odds and Picks for Today, 09/11/25

After splitting the first 2 games of this series, the Rays and White Sox are set for a rubber match on Thursday afternoon. Reliever Ian Seymour will be making his third career start for Tampa Bay. He owns a strong 2.89 ERA on the season and has allowed just 2 earned runs over his last 14.0 innings of work. It would be a bit surprising to see him provide the Rays will length in this one, but the good news is that the Tampa bay bullpen ranks 10th in the league with a 3.71 ERA on the season. Chicago’s offense has been better in recent weeks, but look for Seymour and a strong Tampa Bay offense to limit the damage.

Chicago’s Shane Smith will oppose Seymour on the mound. Smith is putting together a strong rookie campaign, as he owns a 3.95 ERA and 1.20 WHIP through 25 starts and 125.1 innings this season. He has been far better at home, where he is holding opponents to a measly .183 batting average through 12 starts at Rate Field. The Rays aren’t exactly in a groove at the plate right now, as they rank 23rd in baseball with 18 runs and 3 runs per game over the last week. Look to the under in this one.

Rays vs White Sox prediction: Under 8 (+100) available at time of publishing. Playable to -110.

You can bet on our Rays vs White Sox pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!